Fire on Sunday gutted the Brazilian National Museum in Rio de Janeiro, one of Brazil’s oldest.
The cause of the fire, which broke out on Sunday night, was not yet known.
However, no injuries were immediately reported as firefighters struggled to quench the fire.
“This is a tragic day for Brazil. Two hundred years of work and research and knowledge are lost.Brazil President Michel Temer said in a statement.
“This is a cultural tragedy,” the director of the National History Museum said on Globo TV.
The museum was founded in 1818 by King Joao VI and is among Brazil’s most important, with valuable national treasures inside.